5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
CAS: 756526-02-0
Molecular Formula: C34H49NO12
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid - Names and Identifiers
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid - Physico-chemical Properties
| Molecular Formula | C34H49NO12 |
| Molar Mass | 663.75 |
| Density | 1.190±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 781.1±60.0 °C(Predicted) |
| pKa | 4.28±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Physical and Chemical Properties | Bioactive Fmoc-NH-PEG8-CH2CH2COOH is a degradable ADC linker used in antibody drug conjugate (ADC) synthesis. |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid - Uses and synthesis methods
Target
Cleavable
PEGs
in vitro studies
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Last Update：2024-04-10 22:29:15
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid - Reference Information
| biological activity | Fmoc-NH-PEG8-CH2CH2COOH is a degradable ADC linker used for antibody drug conjugate (ADC) synthesis. |
| target | Cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Last Update：2024-04-09 19:05:03
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Product Name: 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester Visit Supplier Webpage Request for quotation
CAS: 756526-02-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 756526-02-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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